PULSAR Phase 2 Study Results This was a very exciting week in the world of pulmonary arterial hypertension. Acceleron announced the results of their PULSAR phase 2 study. This study used Sotatercept, a novel drug, to treat PAH. It was given as a subcutaneous (under the skin) injection every three weeks. The primary endpoint of … [Read more...]
Serotonin and Pulmonary Arterial Hypertension
Serotonin is an important molecule in our bodies. It works in our brain to regulate mood, appetite, sleep, memory and probably many other aspects of our behavior. In the 1960’s and early 1970’s a drug called Aminorex was sold in Europe as a prescription weight loss medication. It was withdrawn from the market in the early 1970’s after doctors … [Read more...]
Getting the Most from the Holiday Season with PAH
The holidays are a time to spend with family and friends and reflect on the past year and think about the upcoming year. This sounds wonderful and low stress. Nothing could be further from the truth. For many people the holiday season is a particularly stressful time of year. While connecting with family can be enjoyable, sometimes our mental … [Read more...]
Pulmonary Hypertension Due To Valvular Heart Disease
As a quick refresher, remember that Pulmonary Hypertension is broadly divided into five groups: Group 1: Pulmonary Arterial Hypertension Group 2: PH due to left heart disease and valvular heart disease Group 3: PH due to chronic lung disease (pulmonary fibrosis or emphysema) Group 4: PH due to chronic blood clots Group 5: PH due to various miscellaneous … [Read more...]
A New Approach to Treating Pulmonary Arterial Hypertension
Historic Treatment of Pulmonary Hypertension For 30 years the focus of treating PAH has been finding medications that dilate (or relax) the pulmonary arteries. This approach has served patients well. The prognosis for patients diagnosed today with PAH is very different from 30 years ago. Today patients can expect to take usually two if … [Read more...]
