On March 26, 2024 the FDA approved sotatercept (brand name of Winrevair), the first new class of medication approved in over a decade. This medication acts by inhibiting signaling in the Activin pathway. A major problem that contributes to PAH for most patients is impaired signaling in the BMPR pathway. You can think of this signaling process as a group of traffic … [Read more...]
Sotatercept Coming Soon
A new drug is poised to enter the PAH market and offers great promise for patients. This new drug works in a completely different way from all the currently approved medications. Sotatercept is an injection (shot) that is given subcutaneously (under the skin) every 3 weeks. The medication acts by blocking activin. In PAH there are good signals and bad signals within the blood … [Read more...]
FAQ’s: Mild Pulmonary Hypertension?
We receive many questions about the significance of an echocardiogram that shows mild “pulmonary hypertension”. When a cardiologist reads an echocardiogram, they often include the finding of pulmonary hypertension. The vast majority of the time this diagnosis has nothing to do with pulmonary arterial hypertension. There are several potential sources of error in using the … [Read more...]
Pulmonary Hypertension Association Registry (PHAR)
A registry is a recording of patients and their characteristics. The PHAR is the first attempt by the PHA to begin to characterize and keep track of PH patients. This ambitious undertaking hopes to be able to identify best practices for the care of PH patients. As the registry matures we will be able to ask scientific questions and test hypotheses. It represents the first … [Read more...]
3 Goals of PAH Fundraising
Why Is There So Much Fundraising for PAH? Pulmonary arterial hypertension is a rare “orphan” disease. The relatively small number of patients living with PAH means that they all need to band together to raise awareness, support each other and raise funds to further research in finding treatments and eventually a cure. What Are The Goals Of Fundraising for PAH? Pulmonary … [Read more...]
