What Is Personalized Medicine?

If you watch the evening news or read the newspaper then there is a good chance that you have heard the term Personalized Medicine.  The most common area where we hear about this is in reference to cancer treatments.  But what does it mean? When your doctor makes a diagnosis, and reaches for a treatment, the doctor is trying to match the best treatment for the individual … [Read more...]

September 2017 Update on Clinical Research Studies for PAH

Despite tremendous progress over the past 20 years, PAH remains an incurable disease. Only through ongoing clinical research trials will we continue to advance the care of PAH patients. Below I highlight some of the ongoing and soon to begin research studies for PAH. Ralinepag This is a molecule that is similar to Uptravi (Selexipag). The phase 2 study was recently completed … [Read more...]

When Should I feel Better After Starting PAH Treatment?

This is a very important question.   Patients with PAH are often very frustrated by feeling poorly, often for one to two years prior to formal diagnosis with PAH.  Once the secure diagnosis is made and treatment is started there is a sense of urgency for both patients and doctors to see tangible evidence of improvement.  Improvement is measured in many different ways.  You may … [Read more...]

New Option for Sub-Cutaneous Drug Delivery Coming Soon

The SteadyMed PatchPump SteadyMed is a new company to the PAH disease state.  They have a novel small subcutaneous pump system (PatchPump) that is being studied for the delivery of Treprostinil (the generic version of Remodulin).  The version of Treprostinil that is included in the pump is called Trevyent and is free of preservatives.   The company just recently reported a … [Read more...]

Update on the Implanted Remodulin Pump

This week we learned that the much-awaited arrival of the Implanted Pump System for Remodulin would be further delayed.  The FDA did not grant Medtronic and United Therapeutics approval.  Details are scant but the announcement indicated that the device might be approved in the beginning of 2018. PAH Patients and doctors alike were let down by the delay.  The delay does not … [Read more...]